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(138) demonstrated that administration of a single dose short-acting GLP-1RA exenatide increased GH levels, whereas administration of long-acting GLP-1RA liraglutide daily for 21 days elicited increased GH levels with no changes in IGF-I levels in healthy subjects

Similar to other neurotrophins, BDNF is first synthesized as a precursor protein, named pro-BDNF of 32 KDa, which is cleaved by different proteases to produce either the mature form of 14 KDa, or the truncated form of 28 KDa

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