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In-vitro (made in the lab) studies also show that Asiaticoside stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis

When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

Insulin is the key that opens the cells to take in the sugar

Conversely, protein levels of GCLM/GCLC (required for GSH biosynthesis), GPX4, and FSP1 were unaffected by dexamethasone pretreatment (Fig