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The hypothesized interactions between each of the measured biomarkers of oxidative stress and damage, mitochondrial dysfunction and inflammation are diagrammed in Figure 5

Abbreviations Ctrl: Control EASE: Expression analysis systematic explorer FDR: False discovery rate GSH: Glutathione GSSG: Glutathione disulfide KO: Knockout MAPK: Mitogen-activated protein kinase MT: Metallothionein PCA: Principal component analysis PHH: Primary human hepatocytes RLU: Relative light units ROS: Reactive oxygen species WD: Wilsons disease References Sandahl TD, Laursen TL, Munk DE, Vilstrup H, Weiss KH, Ott P (2020) The prevalence of wilsons disease: an update

"Glutathione Depletion-Methylation Cycle Block: A Hypothesis For the Pathogenesis of Chronic Fatigue Syndrome"

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