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The variation in the global prevalence significantly increased with country level of income, proportion of males, duration since HIV infection diagnosis, duration on ART, increasing age, and was associated with UNAIDS region (Table 2)

For men, this reduction can lead to a decrease in muscle mass and strength, a diminished sex drive, and potential negative effects on fertility

Additional research is needed on THS to understand the full breadth of potential health effects especially for infants who are likely to place their mouths on objects in their environment, leading to oral exposures of THS compounds

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