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Meanwhile 11.8% of Japanese adults were current users of HTP in 2025, which amounted to 12.9 million people.[19] In contrast, only 2.1 million people in Japan were currently using nicotine vapes in 2025.[20] This is still a significant number of people, but is six times lower than the figure for HTP users, primarily due to the fact that vapes are banned (unless licensed as a medicinal product), while HTP can be legally bought online and in-store

This significantly reduces the production of harmful and potentially harmful chemicals

Additionally, high levels of nicotine lessen the effectiveness of insulin, leading to insulin resistance in response to increased blood glucose

Lung damage: Vaping can cause significant lung damage, similar to the effects of smoking