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If you wanted to prohibit smoking or just cannabis smoking entirely, you can do so

CaMKII-mediated and hyperphosphorylation of ryanodine receptor 2 promotes spontaneous diastolic Ca 2+ leak by increasing ryanodine receptor 2 channel open probability, leading to higher intracellular Ca 2+ levels and the milieu for delayed afterdepolarizations, the most likely trigger for AF initiation

This question can be answered in two ways - you can compare the amount of puffs you get from a cigarette to a vape, or you can compare how much nicotine youre consuming from cigarettes and vapes

While these sounds typically dont warrant immediate action, they shouldnt be dismissed either