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Mice received a regular rodent chow diet (2.99 kcal/g

Clinical trials show consistent reductions in this parameter, with average decreases of 5 to 8 cm reported across studies

Unlike many peptides that act through a single well-defined receptor, GHK-Cu exerts its biological effects through multiple mechanisms including direct stimulation of collagen and glycosaminoglycan synthesis, activation of antioxidant enzymes, modulation of metalloproteinase activity, promotion of angiogenesis, and broad regulation of gene expression across hundreds of genes involved in tissue repair, inflammation, and cellular protection