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We find it in oral form (ampoules, liquid form), as well as in food supplements in the form of capsules or tablets

Upon activation, Nrf2 dissociates from its ligand Keap1 and migrates from the cytoplasm to the nucleus to bind to antioxidant responsive element (ARE)-bearing genes

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Finally, it is proposed that a network of interacting epigenetic mechanisms, including protein synthesis inhibition, oxidative stress and the activation of specific cell signalling pathways is responsible for OTA carcinogenicity [86] (Fig.7) Trichothecenes Trichothecenes (TCs) are mycotoxins produced mostly by members of the genus and other genera (e.g