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PiaggiSMarchiECarnicelliVZucchiRGrieseMHectorAet alAirways glutathione S-transferase omega-1 and its A140D polymorphism are associated with severity of inflammation and respiratory dysfunction in cystic fibrosis

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the P c ir value represents the predicted effective human jejunal permeability of the molecule (Table 10) the predicted P e n- value for dihexa (1.78) is intermediate between the predicted P e ff values for enalapril (1.25) and piroxicam (2.14), two orally bioavailable drugs, dihexa was also predicted to be 22.59 percent unbound to plasma proteins in circulation, thus making it available for distribution into the tissues

However, brands should balance functional outcomes against ingredient cost and shopper price sensitivity