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Fujiki, H., Watanabe, T., Sueoka, E., Rawangkan, A

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Secretion of pro-inflammatory cytokines (IL-6, IL-12, and TNF-) from macrophages was significantly inhibited by ARA-290

GHK, which declines with age, has health promoting effects on many tissues such as chondrocytes, liver cells and human fibroblasts, improves wound healing and tissue regeneration (skin, hair follicles, stomach and intestinal linings, boney tissue), increases collagen, decorin, angiogenesis, and nerve outgrowth, possesses anti-oxidant, anti-inflammatory, anti-pain and anti-anxiety effects, increases cellular stemness and the secretion of trophic factors by mesenchymal stem cells