Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program
For example, if your dose is 2.5 mg per week, a 10 mg vial will last for 4 weeks
Additionally, if you're taking vitamin B12, some medicines can interfere with your ability to digest it, including: Aminosalicylic acid (Paser), used to treat digestive problems Colchicine (Colcrys, Mitigare, Gloperba) is an anti-inflammatory medicine used to prevent and treat gout Proton pump inhibitors (Prilosec, Prevacid) are used to reduce stomach acid Metformin (Glumetza, Fortamet, others), used to treat diabetes Vitamin C supplements QUESTION See Answer What are the warning signs of vitamin B12 deficiency
Human clinical trial activity is emerging but limited