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[PubMed: 16154439] 67

IV therapy can help

Production of PIP 3 enables phosphorylation of Akt at threonine 308 (T308) by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and at serine 473 (S473) by the mechanistic target of rapamycin complex 2 (mTORC2)