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Research has also examined its role in circadian rhythm signaling and melatonin-related pathways , which are central to sleepwake regulation and endocrine timing in experimental systems

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1 2 "F.D.A.'s Approval of a Drug for Autism Upends Review Process"

Melatonin exerts immunomodulatory effects on human ILC2s in a glutathione dependent manner Encouraged by our murine data, which demonstrated that melatonin reprograms ILC2 metabolism and enhances glutathione-dependent immunosuppression, we sought to determine whether these mechanisms also operate in human ILC2s