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Guggul extract contains active plant sterols called guggulsterones, which have been shown to directly stimulate the thyroid gland's iodine uptake and enhance the activity of the 5'-deiodinase enzyme in the liver, thereby significantly boosting the peripheral conversion of T4 to active T3

According to worldwide ethnobotanical studies, approximately 800 plant species are employed for medicinal purposes in preventing diabetes (201, 202)

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