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The process of spermatogenesis takes approximately 74 days from initial cell division to mature sperm release, meaning therapeutic interventions require sustained treatment periods to show measurable outcomes

Intracellular Ca2+ and antioxidant values induced positive effect on fertilisation ratio and oocyte quality of granulosa cells in patients undergoing in vitro fertilisation

They bind to specific receptors on cell surfaces and trigger targeted biological responses

Cancer / proliferation concern: Potentiating c-Met (a proto-oncogene product) raises a legitimate theoretical risk of promoting pre-existing or nascent malignancy