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however, the case-control pair analysis did not show a significantly higher rate of doxycycline treatment in the second and third months of gestation in any group of congenital abnormalities

This study was approved by the Ethic Committee of School of Medicine, University of Zagreb (Project code: 380-59-10106-17-1001290

Dihydrofolate Reductase (DHFR): Three variants affect folate dynamics: 19 bp Intron Deletion: Homozygotes show disrupted tissue folate stores and a twofold increase in risk of spina bifida in offspring

When B12 is used medically, its typically the prescription product Cyanocobalamin injection administered intramuscularly for documented deficiency