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Elevated Cortisol: Hexarelin is capable of raising serum cortisol levels in a dose-dependent manner, and excessive use of hexarelin or other GHS could cause chronically elevated cortisol or hypercortisolism [28, 29]

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Thus, the causal relationship among ER stress induction, pERK1/2, and autophagy activation was examined using MAPK/ERK and ER stress inhibitors, namely U0126 and 4-PBA

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